Skip to product information
1 of 2

Ecological formulas

L-Methylfolate 1000mcg - 100 capsules

L-Methylfolate 1000mcg - 100 capsules

Regular price £27.41
Regular price Sale price £27.41
Sale Sold out
Shipping calculated at checkout.

The L-Methylfolate of the Ecological formula is infused with 5-methyltetrahydrofolate - a highly active variant of folic acid that allows for maximum absorption. With this metabolic form of folate, the most biologically active form of the B vitamin folic acid, you will get the most out of your supplement regimen.

L-Methylfolate (5-MTHF) has emerged as a popular alternative and has been used as a complementary treatment for many who have a genetic MTHFR mutation  and are unable to utilise these nutrients (Folate and Folic acid ) properly.

Any folic acid we ingest must be metabolised (converted) into Dihydrofolate (DHF), Tetrahydrofolate (THF), and then finally into L-methylfolate (5-MTHF) to be used in the body but individuals with mutations cannot complete the final metabolic step that converts folic acid to the active form L-methylfolate (5-MTHF).

Supplementing directly with L-methylfolate bypasses the entire folic acid metabolism cycle allowing absorbtion despite inability to convert folic acid


For those who do not metabolise folic acid well, supplementing L-Methylfolate is the clear alternative while pregnant. Especially if you have a homozygous C677T or A1298C mutation, which is thought to increase your folate requirements even more.

Useful to treat depression in conjunction with other treatments and diabetic neuropathy associated with poorly managed Diabetes.


1 capsule a day  - this is a potent supplement : do not exceed this dosage unless under supervision - important to keep B12 levels within the norm when taking and in general all B vitamins otherwise homocysteine cannot be broken down.

It can interact with several medications - if you take medications please consult your Doctor on the use of this supplement.

View full details